JASS allows for single SNP joint analysis of multiple GWAS summary statistics. Our database currently includes ~150 publicly available GWAS (see next page for the complete list). Three tests have been implemented:
For the moment being, the application is in its early state. E.g., only the omnibus version of the joint analysis is implemented and can be applied on only 64 phenotypes.
JASS: command line and web interface for the joint analysis of GWAS results
Hanna Julienne, Pierre Lechat, Vincent Guillemot, Carla Lasry, Chunzi Yao, Robinson Araud, Vincent Laville, Bjarni Vilhjalmsson, Hervé Ménager, Hugues Aschard
in: NAR Genomics and Bioinformatics, Volume 2, Issue 1, March 2020, lqaa003, https://doi.org/10.1093/nargab/lqaa003
Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms
Hanna Julienne, Vincent Laville, Zachary R. McCaw, Zihuai He, Vincent Guillemot, Carla Lasry, Andrey Ziyatdinov, Amaury Vaysse, Pierre Lechat, Hervé Ménager, Wilfried Le Goff, Marie-Pierre Dube, Peter Kraft, Iuliana Ionita-Laza, Bjarni J. Vilhjálmsson, Hugues Aschard
preprint in: biorxiv, https://www.biorxiv.org/content/10.1101/2020.06.26.172999v1.full